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Study 1 was a multicenter, double-blind, placebo-controlled, study of the pharmacodynamic effects of protonix i.

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Only for intravenous infusionother parenteral routes of administration are not recommended.

Mildtransient transaminase elevations have been observed in clinical studiesThe clinical significance of this finding in a large population of subjects administered Protonix I.Vis unknownsee Adverse Reactions6

Tell your doctor if your condition persists or worsensThe risk of side effects goes up over timeAsk your doctor how long you should take this medication.

Hypersensitivity and Severe Skin Reactionssee Warnings and Precautions5.2Injection Site Reactionssee Warnings and Precautions5.3Potential for Exacerbation of Zinc Deficiencysee Warnings and Precautions5.4Acute Interstitial Nephritissee Warnings and Precautions5.5Clostridium difficileAssociated Diarrheasee Warnings and Precautions5.6Bone Fracturesee Warnings and Precautions5.7Cutaneous and Systemic Lupus Erythematosussee Warnings and Precautions5.8Hepatic Effectssee Warnings and Precautions5.9Hypomagnesemiasee Warnings and Precautions5.10Fundic Gland Polypssee Warnings and Precautions5.11

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